which are thought to account for the vast majority of CM cases, and show a common feature of vascular sequestration of infected erythrocytes (IE) in the brain.[8] There are also some differences, particularly between CM in adults and children, broadly separable into a 'pure' sequestration pattern and IE sequestration with variable (and moderate) vascular pathology. The latter varies from the accumulation of proinflammatory cells such as leukocytes and platelets to localized vascular damage