We recently isolated Zooshikella sp. strain JE-34 from marine
sediment in East China Sea that produce anti-microbial redpigment
prodigiosin . Other strains of Zooshikella sp. are also
known to produce prodigiosin red-pigment . Prodigiosin
red-pigments possess many bioactivities, such as antibiotics,
immunomodulators, anti-diabetic, and anti-cancer activity.
Hence, in the present study Zooshikella sp. strain JE-34 was chosen
as a promising candidate probiotic species and administered in olive flounder against S. iniae through supplementation diets as
a feed additive to assess the innate immune response and disease
resistance of olive flounder for the first time.