There were marked differences in glucose and insulin indices derived from the OGTT and IVGTT. African-Americans were more insulin resistant as measured by the IVGTT compared with the Latino adolescents. However, the well-described hyperinsulinemia in response to iv glucose was not observed after oral glucose in African-American adolescents.
Acute hyperinsulinemia in response to intravenous glucose is not observed after oral glucose ingestion in obese African American adolescents compared to Latino adolescents.