II. What is the difference between a fruit and a vegetable? Well, we know that all fruits bear seeds. Think of an apple or an orange. However, squash, peppers, and tomatoes have seeds in them. Are they fruits? In a scientific sense, they are. However, you wouldn't want to eat them for dessert, as you would an apple or a pear. We don't call them fruits, because they are not sweet, even though, scientifically, they are fruits.