Even though calcium chloride is not a substance you need to monitor closely for health reasons -- it's the sodium, not the chloride, in table salt that leads to high blood pressure -- it still might impact your cooking. For example, when making a tomato sauce, the Food Network recommends avoiding diced canned tomatoes with calcium chloride added as a firming agent. The substance will prevent the tomatoes from breaking down during preparation, leading to a lumpier sauce.