Complicated Urinary Tract Infections, including Pyelonephritis
Zerbaxa is indicated for the treatment of complicated urinary tract infections including pyelonephritis, caused by the following Gram-negative microorganisms: Escherichiacoli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa.
Zerbaxa is supplied as a solution for intravenous infusion. The recommended dosage regimen of Zerbaxa (ceftolozane/tazobactam) for Injection is 1.5 g (1 g/0.5 g) administered every 8 hours by intravenous infusion over 1 hour in patients 18 years or older and with normal renal function or mild renal impairment. The duration of therapy should be guided by the severity and site of infection and the patient’s clinical and bacteriological progress.