between 2003 and 2012 that addressed the problem of the
prognostic stratification of patients with type 1 Brugada ECG
pattern without previous cardiac arrest. Study selection was
first based on the possibility to compare event rates
(incidence of ICD-FVA and SD) in patients with and without
an ICD. Furthermore, articles were selected when they had a
prospective design and included more than 150 patients. The
arbitrary choice of a cutoff of 150 patients was made in order
to exclude small studies, which could be affected by a
selection bias.