3. Medicinal values
I. Anticancer Agent
Cordycepin (3′-deoxyadenosine) exhibits
antimicrobial, anticancer, antimetastatic,
immunomodulatory and insecticidal
effects, and is one of the most important
bioactive anticancer agents found in
Cordyceps species (summer grass-winter
worm). However, due to the requirements
of specific hosts and strict growth
environments, Cordyceps militaris is very
scarce in nature. Therefore, the production
of the anticancer agent cordycepin from
Cordyceps militaris in a large scale is
currently an acute issue that might be
solved by a repeated batch operation of
surface liquid culture[11].
II. Antioxidant activity
Antioxidant activities of CM-hs-CPS2
were evaluated by various methods in
vitro . Results showed that DPPH·
scavenging activity, reducing power and
ferrous ion chelating activity of CM-hs-
CPS2 (8 mg/ml) were 89%, 1.188 and
85%, respectively[12].
III. Improvement of Sperm Production
The present study shows that the CM
supplement increased the total sperm
number, the percentage of motile sperm
cells and normal morphology in subfertile
adult boars. The beneficial effect of CM
supplement continued after stopping the
supplement for 2 weeks. Since plasma
concentration of cordycepin was increased
by the supplementation with CM
mycelium, it is suggested that cordycepin
might be responsible for the increased
semen production and sperm quality in
boars[13].
IV. Anti-influenza Virus Activity
An acidic polysaccharide (APS) was
isolated from the extract of
Cordycepsmilitaris grown on germinated
soybeans. APS might have beneficial
therapeutic effects on influenza A virus
infection at least in part by modulation of
the immune function of macrophages[14].
3. Medicinal valuesI. Anticancer AgentCordycepin (3′-deoxyadenosine) exhibitsantimicrobial, anticancer, antimetastatic,immunomodulatory and insecticidaleffects, and is one of the most importantbioactive anticancer agents found inCordyceps species (summer grass-winterworm). However, due to the requirementsof specific hosts and strict growthenvironments, Cordyceps militaris is veryscarce in nature. Therefore, the productionof the anticancer agent cordycepin fromCordyceps militaris in a large scale iscurrently an acute issue that might besolved by a repeated batch operation ofsurface liquid culture[11].II. Antioxidant activityAntioxidant activities of CM-hs-CPS2were evaluated by various methods invitro . Results showed that DPPH·scavenging activity, reducing power andferrous ion chelating activity of CM-hs-CPS2 (8 mg/ml) were 89%, 1.188 and85%, respectively[12].III. Improvement of Sperm ProductionThe present study shows that the CMsupplement increased the total spermnumber, the percentage of motile spermcells and normal morphology in subfertileadult boars. The beneficial effect of CMsupplement continued after stopping thesupplement for 2 weeks. Since plasmaconcentration of cordycepin was increasedby the supplementation with CMmycelium, it is suggested that cordycepinmight be responsible for the increasedsemen production and sperm quality inboars[13].IV. Anti-influenza Virus ActivityAn acidic polysaccharide (APS) wasisolated from the extract ofCordycepsmilitaris grown on germinatedsoybeans. APS might have beneficialtherapeutic effects on influenza A virusinfection at least in part by modulation ofthe immune function of macrophages[14].
การแปล กรุณารอสักครู่..
