INTRODUCTION
Cancer is a general term applied for series of hateful diseases that may affect different parts of body. These diseases are characterized by a rapid and uncontrolled formation of abnormal cells, which may mass together to form a growth or tumor, or proliferate throughout the body, initiating abnormal growth at other sites. If the process is not arrested, it may progress until it causes the death of the organism. The main forms of treatment for cancer in humans are surgery; radiation and cancer chemotherapeutic agents1. Herbs are staging a comeback and herbal ‘renaissance’ is happening all over the globe. The herbal products today symbolize safety in contrast to the synthetics that are regarded as unsafe to human and environment. Although herbs had been priced for their medicine, flavoring and aromatic qualities for centuries, the synthetic products of the modern age surpassed their importance2. Due to the prevalence, morbidity, and mortality of the malignant diseases, they represent significant medical, social and financial burden on the society. At present the pharmacological therapy of cancer is limited to symptomatic treatments that do not alter the course of the underlying disease. Several Indian medicinal plants have been extensively used in the Indian traditional system of medicine for the treatment of cancer diseases due to their potent pharmacological activity, Low toxicity and less time, economic viability and renewable sources, long history of use, better patient tolerance, public acceptance, cultivation and processing conditions environmental friendly, avoiding environmental pollution by the chemical industry3-11. Research on the anti-cancer benefits of cucumber is still in its preliminary stage and has been restricted thus far to lab and animal studies. Interestingly, however, many pharmaceutical companies are actively studying one group of compounds found in cucumber—called cucurbitacins—in the hope that their research may lead to development of new anti-cancer drugs. Cucurbitacins belong to a large family of phytonutrients called triterpenes. Cucurbitacins A, B, C, D and E have all been identified within fresh cucumber. Eventually, we expect to see human studies that confirm the anti-cancer benefits of cucumbers when consumed in a normal, everyday meal plan12. A second group of cucumber phytonutrients known to provide anti-cancer benefits are its lignans. The lignans pinoresinol, lariciresinol, and secoisolariciresinol have all been identified within cucumber. Interestingly, the role of these plant lignans in cancer protection involves the role of bacteria in our digestive tract. When we consume plant lignans like those found in cucumber, bacteria in our digestive tract take hold of these lignans and convert them into enterolignans like enterodiol and enterolactone. Enterolignans have the ability to bind onto estrogen receptors and can have both pro-estrogenic and anti-estrogenic effects. Reduced risk of estrogen-related cancers, including cancers of the breast, ovary, uterus, and