Controllable degradation of natural biomaterials for tissue engineering is a big issue that has to besolved.
In this paper,sodium alginate was aldehyde-modied and the product (oxidized sodium alginate) was degraded in vitro. Then, oxidized sodium alginate was cross-linked with calcium chloride and its degradation performance was studied. Results showed that the degradation rates of porous materials increased while pH values of degradation liquid decreased, which was proportional to the degree of oxidation. Lotus fibers were carboxyl-modied with TEMPO/NaClO/NaBr system and then lotus nano-bers were obtained. It is found that the degradation rates of the oxidized sodium alginate porous materials which were added lotus nanobers were slow. Thus, the blending porous materials are ex-pected to be used inmedical fields.