In tro d u c tio n
T h e year 2008 w as th e ¯ ftieth an n iversary of th e p u b lication
of a lectu re b y F ran cis C rick in w h ich h e p u t forw
a rd tw o m a jo r co n cep ts: th e C en tra l D o g m a a n d th e
S eq u en ce H y p o th esis [1 ]. T o g eth er w ith D a rw in 's p rin cip
le of n atu ral selection , th ese tw o con cep ts are b elieved
to p rov id e th e u n d erp in n in g to all of b iology. T h e 50th
a n n iv ersa ry o ® ers a n id ea l o p p o rtu n ity to re-eva lu a te
th e va lid ity o f th e C en tra l D o g m a .