2. Production Processes for Purines and Pyrimidines, their Nucleosides and Nucleotides
• 2.1 Purines and deriva-ves
• The purine residue of inosine 5’ –monophosphate (IMP) is built up on a ribose ring in eleven enzymaFcally catalyzed reacFons.
• Ribose phosphate pyrophosphokinase is the first pathway enzyme and catalyzes the conversion of α-D-ribose-5-phosphate (R5P) and ATP to 5-phosphoribosyl-α-pyrophosphate(PRFF).