2. The second mechanisms may be the cariostatic action
of the reaction products between SDF and mineral
component of the tooth. Selvig[35] showed that the
fluoride treatment increased the resistance of the
peri- and inter-tubular dentin to acid decalcification
and as a result, retarded the penetration of acid into
deeper layers of the dentin. Shimooka[36] pointed out
that F− ion of SDF applied to dentin under in vivo