Lactic acid bacteria (LAB) have been used as microbial preservative for thousand of years in order to
extend the shelf life of foods. Bacteriocins produced by Lactococcus species, especially nisin, are widely
used in foods since the LAB have generally been regarded as safe (GRAS) organisms. Nisin has been shown
to effectively inhibit the growth of Gram-positive bacteria, including many important foodborne pathogens.
However, nisin is not widely used in meat products, because of binding of nisin to meat particles in meat
systems (Deegan et al., 2006; O’keeffe and Hill, 1999). Since less activity of bacteriocins in meat products is
expected due to binding of bacteriocin peptide with meat proteins during heat process. Therefore, application
of bacteriocins onto surface of cooked meat products should be an alternative mean of application.