Nowadays due to changes in life styles and with the increased demand for minimally processed foods,studies for packaging of these products gained popularity. Intelligent packaging system, one of the new techniques which is studied in recent years; provides health and safety of the product for the consumer and also monitor the condition of packaged foods to give information about shelf life and regarding the quality of the food during transport and storage. In this technique indicators and sensors(easy to use small devices) are used instead of time consuming, expensive quality measurements for improving the shelf life and providing food safety. In smart packaging system indicators give information about product quality by surrounding conditions and head space gases of packages, also indicators can be attached to the package surface or integrate to packages which are improved for determining metabolite residue formed during storage. Temperature, microbial spoilage, package integrity, physical shock, freshness of the packaged product can be controlled. In this study usage areas and improvements of time-temperature, leakage and freshness indicators which are in intelligent packaging system are explained.