In determining the phase diagram of the maleic acid-caffeine system the choice of solvent is an
important variable In this study, we investigated five solvents: methanol, ethanol, acetone, water, and chloroform It is preferable to find a solvent in which both components have similar, measurable solubilities Thus, we were looking for a solvent that would allow us to use a gravimetric method for solubility measurement and which would avoid extreme asymmetry in the ternary diagram