The dietary inclusion of M. oleifera leaf meal at levels ranging between 1 and 25 g per kg of feed in the starter, grower and finisher diets; did not alter the nutrient composition of the diets. Growth performance, digestibility and yield results indicate that supplementation of M. oleifera leaf meal significantly improved feed utilization efficiency and tissue accretion in broiler chickens used in this study. Furthermore, it may be speculated that the cause for mortality was not due to M. oleifera leaf meal supplementation, since sudden death was observed across all treatment, although during different production periods. Future digestibility studies, at inclusion levels higher than 2.5% are recommended to determine nutrient flow and retention directly from digestive sites until excretion at various growth stages. This would help elucidate the maximum inclusion level and the mode of action of various bioactive compounds in M. oleifera leaves on broiler chicken performance.