Hardy is credited with reforming British mathematics by bringing rigour into it, which was previously a characteristic of French, Swiss and German mathematics. British mathematicians had remained largely in the tradition of applied mathematics, in thrall to the reputation of Isaac Newton (see Cambridge Mathematical Tripos). Hardy was more in tune with the cours d'analyse methods dominant in France, and aggressively promoted his conception of pure mathematics, in particular against the hydrodynamics which was an important part of Cambridge mathematics.
From 1911 he collaborated with John Edensor Littlewood, in extensive work in mathematical analysis and analytic number theory. This (along with much else) led to quantitative progress on the Waring's problem, as part of the Hardy–Littlewood circle method, as it became known. In prime number theory, they proved results and some notable conditional results. This was a major factor in the development of number theory as a system of conjectures; examples are the first and second Hardy–Littlewood conjectures. Hardy's collaboration with Littlewood is among the most successful and famous collaborations in mathematical history. In a 1947 lecture, the Danish mathematician Harald Bohr reported a colleague as saying, "Nowadays, there are only three really great English mathematicians: Hardy, Littlewood, and Hardy–Littlewood."[13]:xxvii
Hardy is also known for formulating the Hardy–Weinberg principle, a basic principle of population genetics, independently from Wilhelm Weinberg in 1908. He played cricket with the geneticist Reginald Punnett who introduced the problem to him, and Hardy thus became the somewhat unwitting founder of a branch of applied mathematics.
His collected papers have been published in seven volumes by Oxford University Press.