(I soon learned that in 1898 Dr. Roswell Park founded the nation’s first research facility devoted exclusively to cancer research at the University of Buffalo).With some trepidation I accepted an offer to fly to Buffalo, see the facilities, and meet faculty. After being convinced I could focus on the research of my choosing while an active member of the graduate program, and after meeting several first-rate researchers such as Kenneth Paigen, David Pressman, Theodore Hauschka and David Harker, I accepted the position. It didn’t hurt that I was offered a salary that was about 50% higher than I had anticipated. The NIH grant application I submitted while in Copenhagen was funded before I arrived in Buffalo, and that, along with some small start-up funding, got me going. The next 2 years were enjoyable personally but painful scientifically.