In general, the literature data show that overexpression of PDOR activity rarely leads to direct improvement in the 1,3-PD final titer,and rather causes alteration of the by-products distribution. The relative production of the oxidative branch metabolites of the glyc-erol catabolism pathway depends on the strain being studied. As described in Ref. [51], different Klebsiella strains vary with respectto the metabolites distribution.