Essential HTN Initially 12.5 mg once daily for 1st 2 days. Maintenance: 25 mg once daily. May increase at 2-wk intervals to a total daily dose of 50 mg once daily or in divided doses. Angina pectoris Initially 12.5 mg bid for 1st 2 days. Maintenance: 25 mg bid. May increase at 2-wk intervals to a total daily dose of 100 mg in divided doses. Symptomatic chronic heart failure Initially 3.125 mg bid for 2 wk. May increase at 2-wk intervals to 6.25 mg bid followed by 12.5 mg bid & 25 mg bid thereafter. Patient >85 kg Max: 50 mg bid, 1 wk, recommence at 3.125 mg bid & titrate dose accordingly