Acute toxicity of Cr (VI) and Cr (III) are different, so the toxic of hexavalent chromium is higher than trivalent chromium. The effects of chromium present mostly via inhalation and ingestion, so chromium can damage respiratory tract pass through inhalation and irritates mucosal tissue, damage cardiac, intestine, hepatic and kidney and potentially death pass through oral. For dermal contact, chromium cause allergy to dermal skin in acute effect. Moreover, chronic effect of chromium can deeply permeability through skin and presents more effect than acute effect (Assem and Zhu, 2007). The main target organ that can absorb chromate is kidney.