Background: Post hepatitis C virus chronic liver disease (CLD) is prevalent among the Egyptian
population with a bad impact upon their quality of life (QOL). Hepatocellular carcinoma (HCC) is
one of the long term and fatal complications of CLD and it also has its negative impact on patient’s
quality of life. Aim: To assess impact of CLD and HCC on the quality of life of group of hospitalized
elderly patients. Methodology: Ninety elderly patients were divided into three groups: 30 elderly
with post hepatitis C virus CLD, 30 elderly with HCC and 30 others free of liver disease as control
group (Cn), all were recruited from the in-patient ward and the outpatient clinic of the Geriatric
Department, Ain-Shams University Hospital. After giving consent, comprehensive geriatric assessment
was done with assessment of their quality of life by using the Short Form-36 health survey
(SF-36). Investigations including liver enzymes, serum albumin, serum bilirubin and abdominal
ultrasound were done. Results: All QOL domains were the highest among control group, followed
by HCC group and the least among CLD group. The differences were statistically significant
in most subscales and total score [Mean of Cn = 81.9 ± 12.4, Mean of CLD = 47.5 ± 21.9, Mean of HCC
= 62.3 ± 16.1; P Cn/CLD ≤ 0.001, P Cn/HCC ≤ 0.001, P CLD/HCC = 0.004]. Albumin was the only biochemical
marker correlated positively with total SF score and two subscales (PF and EF) [r = 0.408;
Background: Post hepatitis C virus chronic liver disease (CLD) is prevalent among the Egyptianpopulation with a bad impact upon their quality of life (QOL). Hepatocellular carcinoma (HCC) isone of the long term and fatal complications of CLD and it also has its negative impact on patient’squality of life. Aim: To assess impact of CLD and HCC on the quality of life of group of hospitalizedelderly patients. Methodology: Ninety elderly patients were divided into three groups: 30 elderlywith post hepatitis C virus CLD, 30 elderly with HCC and 30 others free of liver disease as controlgroup (Cn), all were recruited from the in-patient ward and the outpatient clinic of the GeriatricDepartment, Ain-Shams University Hospital. After giving consent, comprehensive geriatric assessmentwas done with assessment of their quality of life by using the Short Form-36 health survey(SF-36). Investigations including liver enzymes, serum albumin, serum bilirubin and abdominalultrasound were done. Results: All QOL domains were the highest among control group, followedby HCC group and the least among CLD group. The differences were statistically significantin most subscales and total score [Mean of Cn = 81.9 ± 12.4, Mean of CLD = 47.5 ± 21.9, Mean of HCC= 62.3 ± 16.1; P Cn/CLD ≤ 0.001, P Cn/HCC ≤ 0.001, P CLD/HCC = 0.004]. Albumin was the only biochemicalmarker correlated positively with total SF score and two subscales (PF and EF) [r = 0.408;
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