The CA-MRSA ABM models people as agents who go through their daily activities at various places in the metropolitan area, on an hourly basis, and separately for weekdays and weekends. Agents engage in activities that afford possibilities for disease transition, such as self-infection due to an abrasion or injury, or transmission, if other agents are present and have close contact. The model includes a synthetic popula- tion of agents for the metro area based on U.S. Census and other data (Wheaton et al. 2009). Individual places across the area are included in the model, with locations denoted by geographic coordinates. Agents located in the same place and engaged in the same activity at the same time in the simulation pos- sibly have the type of close physical contact with one another that can result in CA-MRSA transmission. They may transition to different disease states through contact or other possible disease state transition pathways.