Figure 1Adjusted odds ratios (ORs) and 95% confidence
intervals (CIs) for diagnosis profiles for travelers aged 60
years and over versus travelers aged 18–45 years of 63,076
ill travelers seen in GeoSentinel clinics between 1997 and
2008. Only significant ORs are presented. Only diagnoses
including at least 45 cases by age group are presented.
Diagnosis profiles are adjusted for sex, reason for travel,
clinical settings, pre-travel advice, and region of exposure.
URTI=upper respiratory tract infection; LRTI=lower
respiratory tract infection; FLI=flu-like illness; HAPE=
high-altitude pulmonary edema; P falciparum malaria=all
cases including complicated malaria; G-PU-O=gastritis,
peptic ulcer, and esophagitis; GERD=gastroesophageal
reflux disease; UTI=urinary tract infection; GI=genital
infection; and STD =sexually transmitted disease. Heart
disease (OR 15.88, CI 11.17–22.87) was not included in the
figure due to the magnitude of the OR.
for potential confounders such as sex, reason for travel,
travel duration and region of travel, pre-travel advice,
clinical settings, and risk level qualifier. We found that
age per se was associated with the distinct patterns of
travel-associated illness observed in older and younger
individuals in all cases with the exception of high-altitude cerebral edema, acute mountain sickness, and
strongyloïdes (Figure 1). Subanalysis in the older group
by age category showed a linear positive relationship
between age and the relative proportion of death, heart
disease, and LRTI, and an inverse relationship between
age and P falciparummalaria and dengue among ill
travelers, with all trends being significant (p
Figure 1Adjusted odds ratios (ORs) and 95% confidence
intervals (CIs) for diagnosis profiles for travelers aged 60
years and over versus travelers aged 18–45 years of 63,076
ill travelers seen in GeoSentinel clinics between 1997 and
2008. Only significant ORs are presented. Only diagnoses
including at least 45 cases by age group are presented.
Diagnosis profiles are adjusted for sex, reason for travel,
clinical settings, pre-travel advice, and region of exposure.
URTI=upper respiratory tract infection; LRTI=lower
respiratory tract infection; FLI=flu-like illness; HAPE=
high-altitude pulmonary edema; P falciparum malaria=all
cases including complicated malaria; G-PU-O=gastritis,
peptic ulcer, and esophagitis; GERD=gastroesophageal
reflux disease; UTI=urinary tract infection; GI=genital
infection; and STD =sexually transmitted disease. Heart
disease (OR 15.88, CI 11.17–22.87) was not included in the
figure due to the magnitude of the OR.
for potential confounders such as sex, reason for travel,
travel duration and region of travel, pre-travel advice,
clinical settings, and risk level qualifier. We found that
age per se was associated with the distinct patterns of
travel-associated illness observed in older and younger
individuals in all cases with the exception of high-altitude cerebral edema, acute mountain sickness, and
strongyloïdes (Figure 1). Subanalysis in the older group
by age category showed a linear positive relationship
between age and the relative proportion of death, heart
disease, and LRTI, and an inverse relationship between
age and P falciparummalaria and dengue among ill
travelers, with all trends being significant (p<0.001)
(Figure 2).
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