The surface confined interaction of TPT and dsDNA was then investigate by using unmodified and SWCNT modified PGEs for 5 min. TPT and guanine signals were measured by using DPV before/after interaction of 0.5 ug/mL dsDNA was performed. The voltammetric detection process was succesfully achieved by using SWCNT-PGEs based on the signal enhancement observed at the signals ofmTPT and guanine. The average signals of TPT and guanine were respectively found to be 3.3 +- 0.9 uA and 5.2 +- 0.7 uA medsured at + 0.79 V and +1.0 V by using SWCNT-PGEs that were 0.3 and 0.8 folds higher than the ones obtained by unmodified PGEs. These results were consistent with the reports presenting of the biomolecular recognition at the surface of CNT, or graphene oxide modified sensor platforms.