After appearance of advanced CPE in the virusinfected
cells, different morphogenetic stages of
the grouper iridovirus were observed in cytoplasm.
The virus particles were never observed
inside the nucleus. At the early stages of virus
infection, the nucleocapsids were presented inside
a cytoplasmic vacuole which were being enlarged
by fusion with intracellular membranes (Fig. 1).
The release of viral nucleoid materials into the
cytoplasm was not observed.