Immobilization systems have been used for high quality beer production. Using immobilization technology could favor the characteristics of beer such as color, flavor, and headspace compounds of stout beer. A comparative study was carried out for beer fermentation by using free and rnicroencapsulated yeast cells in alginate. The velocity of the fermentation was not altered by immobilization. At the end of third day of batch fermentation, the amount of free viable biomass in the bioreactor with microencapsulated yeast had more secondary metabolism activity than free cells. However, immobilization does not alter the sensorial quality of the beer