Specific treatment for the underlying
nerve damage, other than improved glycemic
control, is currently not available.
Glycemic control was shown to effectively
prevent DPN and CAN in type 1
diabetes (60,61) and may modestly
slow progression in type 2 diabetes
(13) but does not reverse neuronal
loss. Therapeutic strategies (pharmacological
and nonpharmacological) for the
relief of specific symptoms related to
painful DPN or autonomic neuropathy
are recommended because they can potentially
reduce pain (62) and improve
quality of life.