The nutritional quality of three sources of rendered meat and bone meals (MBM) was evaluated as feed ingredients in diets for juvenile Litopenaeus vannamei. Two trials were conducted in this work: an in vivo apparent digestibility trial and a growth trial. The apparent digestibility coefficients for dry matter, crude protein and amino acids of diets containing fixed percentages of each protein source were determined using the marker (0.5% chromic oxide) method. A separate feeding trial was conducted to ascertain the maximum level of replacement of high-quality Norwegian fish meal in diets for this species. Nine dry diets were formulated to contain each protein source at 25%, 50% and 75% levels of replacement of fish meal. A 10th diet, the control, contained no meat and bone meal. Fish oil was adjusted to maintain equal lipid levels among the diets. The growth and survival of shrimp fed each diet for 8 weeks were determined.