A recent review of symptoms at EOL identified that the mean number of physical symptoms per child was 6.3 and the most frequently reported symptoms were pain, poor appetite, fatigue, lack of mobility, and vomiting. In this study, patients with brain tumors more frequently reported symptoms of incontinence compared to patients with leukemia or solid tumors. In another study that interviewed parents 4–9 years after the death of their child, more than one third of parents felt their child had unrelieved pain near the EOL and more than half of these parents were still affected by this experience. This further highlights the need for adequate management of physical symptoms.