Data synthesis
We will undertake analysis of the data using Cochrane RevMan
5.2 software (RevMan 2011).Wewill present the results with 95%
confidence intervals (95% CI) and report estimates for dichotomous
outcomes as RR, and continuous outcomes asMDor SMD.
Data synthesis will depend on the quality, design and heterogeneity
of the included trials. If data are not appropriate for pooling
or analysis, we will undertake a narrative overview, which will be
structured according to the study design that has been used.