Drug-loaded silk microneedles fabrication process:
i) Al master is manufactured by high speed milling and chemical wet etching,
ii) PDMS is cast over Al master to produce negative mold,
iii) PDMS mold is removed from Al master,
iv) drug-loaded silk solution is cast over PDMS mold,
v) silk is allowed to dry, and,
vi) drug-loaded silk microneedles are removed from PDMS mold.