It was constructed by the personal budget of Chaophya Abhaibhubejhr in 1909 as a residence for King Rama V on his next royal visit to Prachin Buri. Unfortunately, His Majesty passed away in 1910. King Rama VI and his family stayed here instead during his royal visit in 1912. In 1990, the Department of Fine Arts registered the Chaophya Abhaibhubejhr Building as an ancient monument. It was officially opened on 24 June, 1996, as the Abhaibhubejhr Thai Traditional Medicine Museum, the centre for collection of Thai traditional books, herbs, medicine and local medicine.