In this study, aflatoxin B1 (AfB1) adsorption by reference clays and activated carbon (AC) will be compared to a commercial clay additive, Novasil, that lessens aflatoxicosis in animals. The n-alkylammonium expansion identified Novasil as a low-charge montmorillonite. AC and the montmorillonites, Novasil, SWy-2, and SAz-1 adsorbed ∼200 g/kg AfB1 from water, whereas, sepiolite (SepSp-1) adsorbed only ∼60 g/kg. For AfB1 adsorption from aqueous corn meal, a 60% methanol extraction was used.