3 Etiopathology of AV is multifactorial. Infection Correspondence email to: tonisutono@yahoo.com of Propionibacterium acnes is considered as the main etiology of AV, but the roles of oxidative stress and hormonal influences seem to be important. AV is characterized by excessive sebum production,4 follicular hyperkeratinisation, and increased release of inflammatory chemical substances. Oxidative stress presumably plays an important role in the pathogenesis of AV, because oxidative stress alters the condition of the pilosebaceous unit which originally