The concept of patient safety is not new to CEs. In the past three decades since one of the first in-house clinical engineering departments was conceived and developed, safety has been the mission of such a department. A mission statement of a typical clinical engineering department is: “To assure a cost-effective, safe, quality environment for patients, employees, volunteers, visitors, and medical staff of the hospital, relative to patient care, diagnostic, therapeutic, and life-support medical devices, instruments, and systems.” The American College of Clinical Engineering (ACCE) defines a clinical engineer as: “a professional who supports and advances patient care by applying engineering and managerial skills to heath care technology.” One of the missions of ACCE is “to promote safe and effective application of science and technology in patient care.” Clinical engineers are uniquely positioned to address patient safety issues for the following reasons: