Actinomycetes are filamentous, antibiotics producing
bacteria. They are found in freshwater and marine water
habitats[1-3]. The dominant actinomycetes Micromonospora
can be isolated from aquatic habitats such as streams,
rivers, lake mud, river sediments, beach sands, sponge and
marine sediments[4,5]. Several novel bioactive compounds
were discovered from aquatic actinomycetes, for example
rifamycin from Micromonospora[6]; salinosporamide-A,
an anticancer metabolite from a Salinispora strain
marinomycins from Marinophilus sp.[8]; abyssomicin-C from