tThe present study aims to optimize extraction process of lycopene by using solvents and examine the effect ofenzyme treatment on the recovery if any. Different parts of tomato fruits like whole tomato, peel, pulp and industrialwaste were screened for lycopene content. The extraction of lycopene was carried out with four different solventsto know their extraction efficiency. Two step extraction processes was followed for enzyme-assisted extraction oflycopene. In the first step waste samples were treated with enzymes i.e. cellulase and pectinase, whereas in secondstep extraction of lycopene was carried out by solvent. The optimization study with respect to concentrations andincubation time were carried out for both the enzymes. Also the effect of particle size and cooking methods onrecovery of lycopene were studied. The results revealed that the tomato peel (417.97 g/g) contains highest amountof lycopene followed by industry waste (195.74 g/g), whole tomato (83.85 g/g) and pulp (47.6 g/g). When extractionwas carried out by tri-mixture (i.e. acetone, ethanol and hexane) got higher recovery of lycopene than the othersolvents. Maximum recovery of lycopene was obtained at 1.5% cellulase and 2% pectinase respectively at 4 h ofincubation period. The results also indicated that finer the particle size, higher the recovery of lycopene, whereas allcooking methods reduced the recovery of lycopene. The above extraction process will be beneficial to the small scaleentrepreneur to improve their socio-economical status.