although 4-hydroxycoumarin is a small group in part of coumarin substituted in the pyrone ring widespread interest in this group has been continuously recognized because of it anticoagulant effects
this property has been exploited in pharmaceutical which are used in the treatment of cardiovascular disease
warfarin originally developed as a powerful rodenticide that kills though it haemorrhagic property it useful as a anticoagulant drug and as the most valuable drug in the treatment of bronchial asthma