g (Table 2). Initiation of antihypertensive treat- ment at lower levels (≥140/90 mmHg) is suggested for women with a) gestational hypertension with or without proteinuria, b) pre-existing hypertension with the superimposition of gestational hypertension or c) hypertension with asymptomatic organ damage or symptoms at any time during pregnancy.127The aim of antihypertensive treatment is to prevent complications, such as maternal cerebral haemor- rhage and eclampsia, and allow prolongation of preg- nancy. According to the National Institute of Clinical Excellence (NICE) guideline for “management of hypertensive disorders during pregnancy 2010”, the therapeutic goal in severe PIH is a gradual decrease of blood pressure to <150/100 mmHg.128Methyldopa is considered the drug of choice in pregnancy due to its effectiveness and long safety record. Labetalol can be given intravenously in emer- gency cases. Calcium channel blockers (CCB), such as nifedipine per os or isradipine IV, are effective and have no major teratogenic risk. A potential synergism with MgSO4 that may induce hypotension must be taken into consideration. Atenolol and metoprolol appear to be safe and effective in late pregnancy. Hy- dralazine is no longer the parenteral drug of choice in emergency cases due to perinatal adverse effects and slower therapeutic response.129-132 A Cochrane review about the use of diuretics for prevention of PE and its complications disclosed no significant difference in pregnancy outcomes between the treated group and the placebo or no-drug groups.133 Angiotensin-
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