Results
Colorectal cancer incidence rates for both males and females statistically significantly increased from 1983-87 to 1998-2002 for 27 of 51 cancer registries considered in the analysis. The increases occurred in registries from all parts of the world including Eastern European countries, most parts of Asia, and select countries of South America.
In the European region, the largest increase in colorectal cancer incidence rates from 1983-87 to 1998-2002 occurred in Slovakia, Slovenia, and the Czech Republic (>45% among men and 25% among women; Table 1 ). For those countries with more historical data, these trends are continuations of increases that began in 1963-67 (Fig. 1). The Czech Republic had the highest colorectal cancer rate for males in 1998-2002 of all the 55 registries examined and Slovakia had the 4th highest (Table 1, Supplemental Table S1). The rates for males in these two countries have exceeded the peak colorectal cancer incidence for males observed in long-standing developed nations such as the United States. Registries in Northern Europe such as Norway and Finland showed a slight increase between 11% and 16% among men and women from 1983-87 to 1998-2002, whereas rates in Sweden and Denmark have leveled off (Table 1, Supplemental Fig. S1). Northern European countries were intermediate in their rates of colorectal cancer in 1998-2002 compared with other registries with the exception of Norway and Denmark which had the 8th and 15th highest colorectal cancer rates, respectively, among females (Table 1, Supplemental Table S1).
ResultsColorectal cancer incidence rates for both males and females statistically significantly increased from 1983-87 to 1998-2002 for 27 of 51 cancer registries considered in the analysis. The increases occurred in registries from all parts of the world including Eastern European countries, most parts of Asia, and select countries of South America.In the European region, the largest increase in colorectal cancer incidence rates from 1983-87 to 1998-2002 occurred in Slovakia, Slovenia, and the Czech Republic (>45% among men and 25% among women; Table 1 ). For those countries with more historical data, these trends are continuations of increases that began in 1963-67 (Fig. 1). The Czech Republic had the highest colorectal cancer rate for males in 1998-2002 of all the 55 registries examined and Slovakia had the 4th highest (Table 1, Supplemental Table S1). The rates for males in these two countries have exceeded the peak colorectal cancer incidence for males observed in long-standing developed nations such as the United States. Registries in Northern Europe such as Norway and Finland showed a slight increase between 11% and 16% among men and women from 1983-87 to 1998-2002, whereas rates in Sweden and Denmark have leveled off (Table 1, Supplemental Fig. S1). Northern European countries were intermediate in their rates of colorectal cancer in 1998-2002 compared with other registries with the exception of Norway and Denmark which had the 8th and 15th highest colorectal cancer rates, respectively, among females (Table 1, Supplemental Table S1).
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