a 49-year-old, male, from Upon Ratchathani, a farmer for 30 years with no history of major illnesses or previous
hospitalizations, no history of trauma. No known allergy to food and drugs, nor exposure to toxic chemicals. His
mother and a sister had diabetes mellitus. His illness started 3 weeks prior to admission as pain, swelling, and
limitation of movement of the left shoulder, with intermittent, moderate to high grade fever. Consultation was done
with a private doctor where he was given unrecalled medications, which afforded no relief of symptoms. One day
prior to admission, he had 10 episodes of loose bowel movement, which were watery, non-mucoid, non-blood
streaked, moderate in amounts. He complained of generalized musculoskeletal pain, nausea and headache.
Relatives rush him to a hospital. The patient is a 30 pack-year smoker and an occasional alcoholic drinker.
Physical examination: showed hepatomegaly and right upper quadrant tenderness and slight swelling on the
shoulder, with no limitation of movement, erythema nor tenderness.
Patient was febrile (T range: 39-40°C), with episodes of disorientation, restlessness and hypotension.
Another soft tissue inflammation similar to the one on the left shoulder developed on the right knee followed by
suppurative lesions in the lateral aspect of the right leg, eventually leading to grade II pitting edema.
X-rays of the left shoulder wasnormal while those of the right knee showed beginning osteoarthritic changes.
The patient also had pneumonia. The chest x-ray was read as minimal PulmonaryTB, left upper lobe and bilateral
perihilar pneumonitis