In the year 1996, the first reactive cyclodextrin derivative,namely monochlorotriazinyl-β-cyclodextrin (MCT-β-CD) having a monochlorotriazinyl group as a reactive anchor was introduced for permanent surface modification of textiles.Recently, cellulase enzyme treatment has been done to raise the grafting yield of MCT-β-CD on organic cotton. The inclusion of antibacterial agent thymol on biopolished MCT-β-CD grafted fabric has shown high efficiency against Staphylococcus aureus and Escherichia coli. Durability to the antibacterial property was maintained up to several repeated washing cycles by the treatment.