The elevated _VE responses concur with previous studies during both submaximal running and cycling exercise.
As with the V_ O2 response, the differing time course of _VE and f R during running and cycling after EIMD was not hypothesized and is difficult to explain. However, the following are offered as possible contributing factors. In
contrast to cycling, running utilizes the SSC, and there is strong evidence that the stretch reflex has a vital role in SSC activity and contributes to force generation between eccentric and concentric phases. The reduction in stretch-reflex sensitivity following muscle damage is thought to be mediated by the activation of fine myelinated (Group III) and unmyelinated (Group IV) afferent fibers.These small afferents could also exert a significant influence on _VE during dynamic exercise.
Therefore, it is possible that activation of Group III and IV afferents inhibiting stretch-reflex sensitivity as a consequence of
EIMD may have led to the early augmentation of _VE during running. Group III and IV afferent fibers are often described as
being polymodal, in that they are sensitive to several parameters associated with fatigue or muscle damage. Muscle pain has also been shown to provoke an increased ventilatory response through activating nociceptive muscle afferents.56e58 Therefore, such pain (soreness) following the squatting exercise might have also stimulated afferent fibers, contributing to the increased ventilatory response during running and cycling. Furthermore, the heightened muscle soreness response after 48 hours could have been responsible for the increase in _V E and f R during cycling after 48 hours.
The elevated _VE responses concur with previous studies during both submaximal running and cycling exercise.
As with the V_ O2 response, the differing time course of _VE and f R during running and cycling after EIMD was not hypothesized and is difficult to explain. However, the following are offered as possible contributing factors. In
contrast to cycling, running utilizes the SSC, and there is strong evidence that the stretch reflex has a vital role in SSC activity and contributes to force generation between eccentric and concentric phases. The reduction in stretch-reflex sensitivity following muscle damage is thought to be mediated by the activation of fine myelinated (Group III) and unmyelinated (Group IV) afferent fibers.These small afferents could also exert a significant influence on _VE during dynamic exercise.
Therefore, it is possible that activation of Group III and IV afferents inhibiting stretch-reflex sensitivity as a consequence of
EIMD may have led to the early augmentation of _VE during running. Group III and IV afferent fibers are often described as
being polymodal, in that they are sensitive to several parameters associated with fatigue or muscle damage. Muscle pain has also been shown to provoke an increased ventilatory response through activating nociceptive muscle afferents.56e58 Therefore, such pain (soreness) following the squatting exercise might have also stimulated afferent fibers, contributing to the increased ventilatory response during running and cycling. Furthermore, the heightened muscle soreness response after 48 hours could have been responsible for the increase in _V E and f R during cycling after 48 hours.
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