In community dwelling elderly participants from the ThreeCity
Study, there was some heterogeneity in the association
between lipids and future CHD, according to the lipid-lowering
treatment received at baseline. In those who did not receive any
lipid-lowering treatment, LDL cholesterol, non-HDL cholesterol,
ApoB100, ApoB/ApoA1 and LDL/HDL cholesterol ratios were all
predictors of CHD over 4 years, independently of other traditional
risk factors and hs-CRP. Among those who received statin therapy
(11.5% of the study cohort), the same lipid parameters were predictors
of CHD, but in general with greater strength. In those who
were on fibrates (13% of the study cohort), only triglycerides were
independent predictors of CHD
In community dwelling elderly participants from the ThreeCityStudy, there was some heterogeneity in the associationbetween lipids and future CHD, according to the lipid-loweringtreatment received at baseline. In those who did not receive anylipid-lowering treatment, LDL cholesterol, non-HDL cholesterol,ApoB100, ApoB/ApoA1 and LDL/HDL cholesterol ratios were allpredictors of CHD over 4 years, independently of other traditionalrisk factors and hs-CRP. Among those who received statin therapy(11.5% of the study cohort), the same lipid parameters were predictorsof CHD, but in general with greater strength. In those whowere on fibrates (13% of the study cohort), only triglycerides wereindependent predictors of CHD
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