ADDITIONAL CONSIDERATIONS
There are a number of other issues that need further exploration
in health care-associated pneumonia. First, certain
combinations of health care-associated pneumonia guideline-concordant
therapy do not provide coverage for atypical
pathogens. In community-acquired pneumonia, the need
for atypical coverage has been a matter of debate for more
than a decade.33-35 In health care-associated pneumonia,
concerns for atypical pathogens remain and some clinicians
may add a macrolide to any health care-associated pneumonia
regimen without atypical coverage, citing both the risk
of atypical pathogens and the anti-inflammatory potential of
macrolides.7,36