4. Conclusion
In conclusion, we have developed an electrochemical method
of cholesterol detection using β-CD functionalized graphene. The
detection limit of cholesterol is achieved as low as 1 mM which is
quite impressive compared to recent literatures. Salient features of
the present study include: (1) Graphene's increased solubility after
β-CD functionalization, due to the covalent interactions occurring
between the hydrophilic surfaces of the two; (2) The sensor can
easily detect cholesterol using DPV technique, where cholesterol
molecule is replacing MB molecule and forming the inclusion
complex within the hydrophobic core of Grp-β-CD. Also, the
developed detection method is important as it does not use any
enzyme or antibody for detection and still, detects cholesterol
efficiently in the micro molar concentration range with outstanding
selectivity over the common interfering species