A gene (MoPRD1), related to xylose reductases, was identified in Magnaporthe oryzae. Recombinant MoPRD1 displays its highest specific reductase activity toward l-arabinose and d-xylose. Km and Vmax values using l-arabinose and d-xylose are similar. MoPRD1 was highly overexpressed 2–8 h after transfer of mycelium to d-xylose or l-arabinose, compared to d-glucose.