Stem Cell Treatment for Alzheimer’s Disease
Widespread nonspecific neuronal death in the brain of patients with AD makes stem cell‑based therapy for restoration incredibly challenging. Stem cell therapy is characterized by the differentiation potential of implanted cells into multiple cellular lineages, based on their proliferative capacity, neurotrophin secretion, promotion of neovascularization, anti‑inflammatory activity, and neurotrophic, and neuro‑protective activity.[33] The therapeutic strategies of stem cell implantation involve inducing activation of endogenous stem cells and regenerating the injured cells through stem cell transplantation.